Mewtwo is a Psychic type Pokemon that was introduced in Generation I. It is known as the “Genetic Pokemon” because it was created by science. Mewtwo is considered one of the strongest Pokemon in the game and is often used in competitive play. However, there are a few Pokemon that can take it down.

One of the best attackers against Mewtwo is Tyranitar. Tyranitar is a Rock/Dark type Pokemon that was introduced in Generation II. It is known as the “Armor Pokemon” because of its tough hide. Tyranitar is a very powerful Pokemon and can take down Mewtwo with ease.

Another good attacker against Mewtwo is Machamp. Machamp is a Fighting type Pokemon that was introduced in Generation I. It is known as the “Superpower Pokemon” because of its great strength. Machamp can easily take down Mewtwo with its powerful attacks.

So, if you’re looking for a good Pokemon to take on Mewtwo, Tyranitar and Machamp are two of the best choices.

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Follow This Table For Choosing The Right on For The Best Attackers Against Mewtwo

Review of The10 Best Attackers Against Mewtwo Reviews with Features

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Important Aspects to Consider When Choosing Attackers Against Mewtwo

Assuming you are asking for a guide on the best attackers against Mewtwo in Pokémon GO, here are some recommended attackers:

1. Machamp: With a massive attack stat and the ability Guts, Machamp is a formidable opponent for Mewtwo.

2. Dragonite: Another top-tier attacker, Dragonite boasts a massive attack stat and the ability Inner Focus, making it a tough customer for Mewtwo.

3. Gyarados: A massive powerhouse, Gyarados is a great option against Mewtwo thanks to its massive attack stat and the ability Intimidate, which lowers the opponent’s attack stat.

4. Tyranitar: A massive behemoth, Tyranitar is a great choice against Mewtwo thanks to its massive attack stat and the ability Sand Stream, which raises the Sandstorm weather condition.

5. Houndoom: A great Dark-type attacker, Houndoom is a solid choice against Mewtwo thanks to its good attack stat and the ability Flash Fire, which makes it immune to Fire-type attacks.

Frequently Asked Questions

1. Which attackers are best against Mewtwo?

There are a few different attackers that are considered to be the best against Mewtwo. These include Machamp, Dragonite, Gyarados, and Tyranitar. Each of these attackers has a specific set of moves and abilities that make them particularly effective against Mewtwo.

2. What is the best strategy for defeating Mewtwo?

There is no one-size-fits-all strategy for defeating Mewtwo. Each of the best attackers against Mewtwo has a different set of moves and abilities, so the best strategy for defeating Mewtwo will vary depending on which attacker you are using.

3. How do I know if my attacker is effective against Mewtwo?

The best way to determine if your attacker is effective against Mewtwo is to consult a reliable Pokémon battle simulator. This will allow you to input your attacker’s moveset and abilities, and see how they fare against Mewtwo in a simulated battle.


Mewtwo is a Psychic type Pokemon, and is vulnerable to Bug, Ghost and Dark type attacks. The best attackers against Mewtwo are Tyranitar, Weavile and Houndoom.

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